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- (1)
- (1)
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- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Ccc R08 | 2919019-72-8 | 98.87% | 414.84 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Ccc_R08 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. It can be used in the study of HBV virus (hepatitis B virus) infection.
- Reduces cccDNA, protein-free RC-DNA, and double stranded linear DNA (DL-DNA) levels in HepDES19 cells.
- Decreases serum levels of pgRNA in a dose-dependent manner.
- Leads to the clearance of cccDNA from HBVcircle mouse livers.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Promega Corporation TLR BIOASSAY CELLS
PRGA1322 TLR BIOASSAY CELLS
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Cayman Chemical RBromoenol lactoned7
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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An internal standard for the quantification of (R)-BEL by GC- or LC-MS
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Retagliptin (SP2086) | 1174122-54-3 | 98.5% | 464.36 | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Retagliptin (SP2086) is a selective, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It can be used for type 2 diabetes mellitus (T2DM) research. Retagliptin inhibits the degradation of GLP-1, thereby amplifying the incretin effect.
- Selective, competitive, and orally active DPP-4 inhibitor.
- Used for type 2 diabetes mellitus (T2DM) research.
- Inhibits the degradation of GLP-1.
- Appearance: Solid, white to light yellow.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 4',5-Dihydroxyflavone | 6665-67-4 | 254.24 | 25 MG
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4',5-Dihydroxyflavone (Compound 2c; Compound B3) is a flavonoid compound. It can inhibit various oxidases, with IC50 values of less than 1 μM for collagenase A (ColA) and 66 μM for α-glucosidase. Its Ki value for soybean lipoxygenase-1 (LOX-1) is 102.6 μM. This compound is suitable for studies on anti-toxicity and anti-diabetes. 4',5-Dihydroxyflavone is also a potent inhibitor of ColA, a bacterial virulence factor that aids bacterial spread by degrading host collagen proteins.
- Type of flavonoid compound.
- Inhibits various oxidases.
- IC50 values for collagenase A (ColA) and α-glucosidase are < 1 μM and 66 μM, respectively.
- Ki value for soybean lipoxygenase-1 (LOX-1) is 102.6 μM.
- Can be used in studies on anti-toxicity and anti-diabetes.
- Potent inhibitor of ColA, a bacterial virulence factor.
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Medchemexpress LLC (R)-Elsubrutinib (Synonyms: (R)-ABBV-105) | 1643570-23-3 | 98.0% | 297.35 | 1 MG
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(R)-Elsubrutinib, also known as (R)-ABBV-105, is an inhibitor of Btk (Bruton's tyrosine kinase). It is intended for use in research related to various immune diseases and cancer. Potential applications include studies for conditions such as rheumatoid arthritis, psoriasis, ankylosing spondylitis, asthma, and systemic lupus erythematosus.
- Target: Btk inhibitor
- Applications:
- Immune diseases (e.g., rheumatoid arthritis, psoriasis, ankylosing spondylitis, asthma, systemic lupus erythematosus)
- Cancer
- Research use: For research purposes only; not sold to patients.
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Cayman Chemical DmyoInositol1 3 5triphosphate
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A synthetic, pure phosphoinositol for signal transduction research; 50-fold less potent than Ins(1,4,5)P3 at initiating calcium release when injected into Xenopus oocytes when tested as the meso compound
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Medchemexpress LLC Exo2 | 304684-77-3 | 99.57% | 354.43 | 1 ML
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Exo2 is a secretion inhibitor that perturbs the trafficking of Shiga toxin between endosomes and the trans-Golgi network. It blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network). Exo2 can also stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells.
- Perturbs Shiga toxin trafficking
- Blocks secretory cargo exit from ER
- Disrupts the Golgi apparatus
- Stimulates calcium-dependent exocytosis
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Medchemexpress LLC NKG2DL2 Human HEK2 50ug
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Recombinant human NKG2DL2 extracellular domain (residues G26-S217), expressed in HEK293 cells and supplied lyophilized with a C-terminal 6xHis tag. The protein activates the KLRK1/NKG2D receptor, does not bind β2-microglobulin, and is provided at high purity for use in NK cell biology, receptor-ligand interaction studies, and related research applications.
- Expressed in HEK293 cells with a C-terminal His tag.
- Contains residues G26-S217 representing the extracellular domain.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Activates KLRK1/NKG2D receptor for NK cell functional assays.
- Lyophilized formulation for stable, long-term storage.
- Reconstitution guidance: do not reconstitute below 100 μg/mL; aliquot and freeze for extended storage.
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Medchemexpress LLC Gastrin-71 Mouse H 2ug | 2ug
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Gastrin-71 protein acts as a potent stimulator of various physiological processes It activates the gastric mucosa promotes the production and secretion of hydrochloric acid and induces the release of digestive enzymes from the pancreas Gastrin-71 Protein Mouse (HEK293 Fc) is the recombinant mouse-derived Gastrin-71 protein expressed by HEK293 with C-hFc labeled tag
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Medchemexpress LLC Benzyldimethyltetradecylammonium-d7 (chloride) | 1219178-72-9 | 95.1% | 375.08 | C23H35D7ClN | 5 MG
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Benzyldimethyltetradecylammonium-d7 (chloride) is the deuterium-labeled isotopologue of benzyldimethyltetradecylammonium chloride supplied as the chloride salt. It is intended for research use as a stable isotope-labeled reference standard or tracer in mass spectrometry and analytical workflows. Solid, off-white powder with reported purity of 95.1%.
- Deuterium-labeled quaternary ammonium chloride for use as an internal standard.
- Suitable for mass spectrometry and tracer studies.
- Molecular formula C23H35D7ClN and molecular weight 375.08.
- Supplied as a solid powder with reported purity of 95.1%.
- Recommended storage: 4°C sealed; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- CAS number 1219178-72-9 for unambiguous identification.
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Medchemexpress LLC Dectin-1/CLEC7A protein, human, Fc fusion | >95.0% | 100UG
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Recombinant human Dectin-1/CLEC7A Fc fusion protein containing the C-type lectin domain. Produced in HEK293 cells and supplied purified for use in ligand binding studies, receptor characterization, and assay development. The Fc fusion increases stability and enables easy detection or immobilization in immunoassays.
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Medchemexpress LLC Pritelivir | 348086-71-5 | C18H18N4O3S2 | 100 MG
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Pritelivir (AIC316) is an antiviral agent that functions as an inhibitor of the viral helicase-primase complex. This mechanism of action allows it to exhibit antiviral activity both in laboratory settings (in vitro) and in animal models of herpes simplex virus (HSV) infection. It is specifically active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2).
- Inhibits the viral helicase-primase complex.
- Demonstrates antiviral activity in vitro and in animal models of HSV infection.
- Effective against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2).
- Exhibits an IC50 of 0.02 μM against HSV1-2.
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Medchemexpress LLC Rilogrotug 25mg | 25mg
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Rilogrotug (AV-380) is a humanized IgG1 monoclonal antibody targeting GDF15[1]
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Medchemexpress LLC Acetarsol | 97-44-9 | 98.6% | 500 MG
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Acetarsol (Stovarsol) is a potent and orally active anti-infective agent. It shows anti-parasite activity and has the potential for the research of proctitis.
- Potent and orally active anti-infective agent.
- Shows anti-parasite activity.
- Potential for proctitis research.
- Soluble in DMSO.
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